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The term pernicious anaemia itself can lead to confusion among clinicians, because there is not always an anaemia, macrocytosis or raised mean corpuscular volume at first presentation[2]

GR predominantly mediates feedback regulation under conditions of elevated circulating cortisol, whereas MR is mainly involved in basal feedback control (de Kloet et al., 2005)

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Two-stage phase II oncology designs using short-term endpoints for early stopping